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Stock impact report

Cabaletta Bio Reports Positive Initial Clinical Data from Phase 1/2 RESET-Myositis™ and RESET-SLE™ Trials of CABA-201 [Yahoo! Finance]

Cabaletta Bio, Inc. (CABA) 
Company Research Source: Yahoo! Finance
– CABA-201 exhibited anticipated profile of CAR T cell expansion and contraction with complete B cell depletion observed in both patients by day 15 post-infusion – – Improvements in both patients' specific disease measures, consistent with academic experience of a similar 4-1BB CD19-CAR T, suggest emerging clinical benefit with CABA-201 while discontinuing all disease-specific therapies other than a planned steroid taper in one patient – – Immature, naïve B cell repopulation in first IMNM patient observed at week 8 consistent with a potential immune system reset – – 18 sites open and recruiting across four Phase 1/2 RESET™ trials with 5 patients enrolled as of June 12, 2024; initial clinical and translational data support continued development of CABA-201 at the current dose – – Company to host live investor conference call and webcast today at 8:00 a.m. ET – here “We are encouraged by the initial safety, clinical and translational data from the RESET-Myositis and RESET-S Show less Read more
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