Bavarian Nordic's mpox vaccine to be trialled in pregnant women and infants [Yahoo! Finance]
BAVARIAN NORDIC R/I S/ADR (BVNRY)
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Source: Yahoo! Finance
The Phase III trial (PregInPoxVac) will enrol around 350 pregnant women and 250 children aged two years and under to assess the safety and immunogenicity of the MVA-BN vaccine in these populations. The trial is being conducted in the Boende territory of the Democratic Republic of Congo (DRC), the country at the epicentre of the fast-spreading outbreak declared by the World Health Organization (WHO) as both a continental and global public health emergency. The trial is due to begin early next year. The randomised controlled trial will evaluate patients over 12 months. In the first stage of the study, two doses of the Jynneos vaccine will be administered to pregnant women before or after birth. Blood samples and breast milk will be collected from a group of mothers and their infants to assess whether maternal antibodies are passed onto the newborn following vaccination via either of these routes. In the trial's second stage, infants aged six to 24 months old will receive a full or
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