Recludix Pharma to Present Data Demonstrating its Oral STAT3 Inhibitor has Differentiated Efficacy and Safety as Compared to JAK/TYK2 Inhibition in In Vivo Models of Inflammatory Arthritis...
Blueprint Medicines Corporation (BPMC)
Last blueprint medicines corporation earnings: 2/13 07:00 am
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Source: Yahoo! Finance
-STAT3 inhibition does not impair the interferon-mediated antiviral defense or hematopoietic growth factor signaling, as seen with JAK/TYK2 inhibitors SAN DIEGO, Nov. 14, 2024 (GLOBE NEWSWIRE) -- Recludix Pharma, a leader in discovery of inhibitors of challenging targets for inflammatory disease, today announced pre-clinical inflammatory arthritis data for REX-7117, an oral, reversible, SH2 domain-targeting STAT3 inhibitor, will be presented at the American College of Rheumatology (ACR) Convergence meeting being held November 14–19, 2024 in Washington, D.C. In multiple in vivo models of inflammatory arthritis, REX-7117 achieved deep, durable, and selective STAT3 inhibition, decreased inflammatory biomarkers such as c-reactive protein (CRP), and achieved statistically significant efficacy compared to vehicle and comparable efficacy to a high-dose of the JAK inhibitor, baricitinib. Unlike both JAK1/2 and pan-JAK inhibitors, REX-7117 did not impair innate interferon-dependent viral re
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- Blueprint Medicines Co. (NASDAQ: BPMC) had its "market outperform" rating re-affirmed by analysts at JMP Securities. They now have a $125.00 price target on the stock.MarketBeat
- Blueprint Medicines Co. (NASDAQ: BPMC) had its "buy" rating re-affirmed by analysts at Needham & Company LLC. They now have a $135.00 price target on the stock.MarketBeat
- Blueprint Medicines Co. (NASDAQ: BPMC) had its "buy" rating re-affirmed by analysts at HC Wainwright. They now have a $135.00 price target on the stock.MarketBeat
- Blueprint Medicines Co. (NASDAQ: BPMC) had its "outperform" rating re-affirmed by analysts at Wedbush. They now have a $135.00 price target on the stock.MarketBeat
- Blueprint Medicines Co. (NASDAQ: BPMC) is now covered by analysts at JPMorgan Chase & Co.. They set an "overweight" rating and a $126.00 price target on the stock.MarketBeat
BPMC
Earnings
- 10/30/24 - Beat
BPMC
Sec Filings
- 11/21/24 - Form 144
- 11/20/24 - Form 144
- 11/14/24 - Form SC
- BPMC's page on the SEC website