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0 -0.000237416904083692 0.00071225071225057 -0.000474833808167216 -0.000474833808167216 -0.00296771130104463 -0.00534188034188037 -0.00189933523266869
Stock impact report

FDA Approves Bristol Myers Squibb's Combination Therapy For Colorectal Cancer Patients With Certain Type Of Gene Mutation [Yahoo! Finance]

Bristol-Myers Squibb Company (BMY) 
Last bristol-myers squibb company earnings: 2/6 07:05 am Check Earnings Report
US:NYSE Investor Relations: bms.com/investors.html
Company Research Source: Yahoo! Finance
targeted treatment option for adult patients with KRASG12C -mutated locally advanced or metastatic colorectal cancer (CRC), who have received prior treatment with fluoropyrimidine-, oxaliplatin-, and irinotecan- based chemotherapy This indication is approved under accelerated approval based on objective response rate (ORR) and duration of response (DOR) results. Bristol Myers Squibb added adagrasib via its $5 billion Mirati Therapeutics Inc. deal The approval is based on results from cohorts of the Phase 1/2 KRYSTAL-1 open-label study, which evaluated Krazati (600 mg tablets administered orally twice daily) in combination with cetuximab in 94 patients with heavily pretreated CRC harboring a KRASG12C mutation. The study met its primary endpoint, with a confirmed ORR of 34% for Krazati with cetuximab, all of which were partial responses. The median DOR, one of the secondary endpoints, was 5.8 months. Current late-line standard of care options results in limited response rate Show less Read more
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