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0.000201979398101353 -0.000100989699050748 -0.000357503534639566 0.000706927893354809 0.00151484548576037 -0.00989699050696833 -0.00989699050696833 -0.00989699050696833
Stock impact report

Centessa Pharmaceuticals a new buy at B Riley on sleep disorders pipeline [Seeking Alpha]

Bristol-Myers Squibb Company (BMY) 
Last bristol-myers squibb company earnings: 2/6 07:05 am Check Earnings Report
US:NYSE Investor Relations: bms.com/investors.html
Company Research Source: Seeking Alpha
The firm has a $33 price target (~110% upside based on Sept. 18 close). Centessa has two orexin 2 receptor agonists in development: ORX750 in phase 1 for sleep-wake disorders -- with phase 2 expected to begin in Q4 -- and ORX142 in the preclinical stage for excessive daytime sleepiness. The company's lead candidate, in registrational phase, is SerpinPC, a subcutaneous biologic for hemophilia B. With the two sleep candidates derisked and with best-in-class potential, analyst Mayank Mamtani says that ORX750 could become a major player in the rare hypersomnia market currently valued at more than $5B. "We believe [total addressable market] expansion into broader neurodegenerative/psychiatric disorders, via follow-on molecule ORX142's progression through preclinical and IND-enabling studies, could further reset CNTA's valuation floor to levels seen in recent major pharma deals," Mamtani wrote, citing Bristol Myers Squibb ( BMY ) and AbbVie acquisitions of, respectively, Karuna The Show less Read more
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