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Stock impact report

AbbVie's atogepant set to reach projected worth of $766m in 2026 after accepted NDA from FDA [Yahoo! Finance]

Biohaven Ltd. Common Shares (BHVN) 
Last biohaven ltd. common shares earnings: 2/25 04:45 pm Check Earnings Report
US:NYSE Investor Relations: investors.biohavenpharma.com
Company Research Source: Yahoo! Finance
Atogepant is a member of the gepant class of drug and is a calcitonin gene-related peptide (CGRP) receptor antagonist. CGRPs are potent vasodilators, particularly in the cerebral circulation. The release of CGRP within the trigeminal nucleus caudalis facilitates activation of nociceptive second-order neurons and glial cells, which leads to the pain associated with migraines. Atogepant is administered orally, which is a key attribute that will significantly strengthen AbbVie's position in the migraine market over the coming years. The NDA approval was supported by data from a pivotal Phase III ADVANCE multi-center clinical trial in patients who experienced four to 14 migraine episodes per month, a pivotal Phase IIb/III study, and a Phase III long-term safety study. In the ADVANCE study, investigators found a greater than 50% reduction in the mean monthly migraine days over a 12-week treatment period, achieving the key primary and secondary endpoints of the study. This mirrored the p Show less Read more
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