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Stock impact report

BBOT Announces First Patient Dosed with BBO-11818, a PanKRAS Dual Inhibitor, in the Phase 1 KONQUER-101 Trial for Advanced Solid Tumors

BridgeBio Pharma, Inc. (BBIO) 
Last bridgebio pharma, inc. earnings: 3/2 08:29 am Check Earnings Report
Company Research Source: Business Wire
The first patient has been dosed with BBO-11818 in the KONQUER-101 first-in-human clinical studyBBO-11818 is an orally bioavailable small molecule panKRAS dual (“ON” and “OFF” states) inhibitor that directly binds to KRAS with picomolar affinityBBO-11818 is expected to provide significant benefit to patients with tumors driven by these oncogenes by safely achieving optimal target inhibition SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--TheRas, Inc. d/b/a BridgeBio Oncology Therapeutics (“BBOT” or the “Company”), a clinical-stage biopharmaceutical company focused on RAS-pathway malignancies, today announced that the first patient has been dosed with BBO-11818 in the Phase 1 KONQUER-101 trial for advanced solid tumors. BBO-11818 is an orally bioavailable small molecule dual inhibitor that directly binds to both the “ON” and “OFF” states of KRAS. KONQUER-101 will enroll patients globally with certain KRAS mutations.“The dosing of the first patient is a major milestone in assessing BBO Show less Read more
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