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Stock impact report

BrainTransporter™ dramatically improves antibody delivery to the brain

Barnes Group, Inc. (B) 
Last barnes group, inc. earnings: 4/24 06:30 am Check Earnings Report
Company Research Source: PR Newswire
STOCKHOLM, Nov. 6, 2024 /PRNewswire/ -- BioArctic AB (publ) (NASDAQ: BIOA B) (STOCKHOLM: BIOA B) has presented the design of its proprietary BrainTransporter (BT) platform at the 16th annual Protein & Antibody Engineering Summit (PEGS) conference in Barcelona, Spain. The BT platform uses active Transferrin Receptor (TfR)-mediated transport, enabling up to 70-fold higher penetration of antibodies over the blood brain barrier, without negative effects on hematological safety parameters.During the 16th annual Protein & Antibody Engineering Summit (PEGS) Europe conference, Dr. Per-Ola Freskgård, VP Science & Technology at BioArctic, presented for the first time the design of the proprietary BT platform as well as validation in preclinical models.Brain uptake of biotherapeutics such as antibodies and enzymes is severely limited by the blood brain barrier (BBB) primarily due to their size. Active transport across the BBB, using one of the body's own delivery mechanisms, aims to enable bette Show less Read more
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