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0.00932668966398361 -0.00357736041906225 0.0284911204803884 -0.00894340104765556 -0.0417784591797623 -0.0803628465567905 -0.0359013670627316 -0.0746135173118692
Stock impact report

Azitra screens first subject in Phase Ib trial of ATR-12 for Netherton syndrome [Yahoo! Finance]

Azitra Inc (AZTR) 
Company Research Source: Yahoo! Finance
The patient is expected to commence treatment by the end of the month. This multi-centre, randomised, double-blind, vehicle-controlled study will involve approximately 12 adults with Netherton syndrome. Participants will receive topical ATR-12 or vehicle control on opposite sides of the body twice daily for 14 days, with a dosage of 10?CFU/g. Azitra founder and COO Travis Whitfill said: “Enrolling the first patient in our Phase Ib trial of ATR-12 will mark a significant milestone for Azitra and, more importantly, for patients suffering from Netherton syndrome, who currently have limited treatment options. “Our recent preclinical data demonstrate ATR-12's potential to effectively deliver an active LEKTI subunit into the skin and address the underlying mechanisms of Netherton syndrome.” Evaluating the safety and tolerability of the asset are the trial's primary endpoints while secondary and exploratory objectives include assessing efficacy signals, biomarkers, pharmacodynamic Show less Read more
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