Azitra doses first subject in Phase Ib Netherton syndrome treatment trial [Yahoo! Finance]
Azitra Inc (AZTR)
Company Research
Source: Yahoo! Finance
This trial plans to enrol approximately 12 adults who will receive the treatment twice daily for 14 days. The company previously screened the first subject in its Phase Ib trial of ATR-12 for treating Netherton syndrome. The primary goals are to assess the safety and tolerability of the topical ATR-12 treatment while secondary objectives will focus on evaluating efficacy signals, biomarkers, and skin pharmacokinetics of the LEKTI subunit. Exploratory objectives, such as pharmacodynamic parameters, biomarkers, anti-LEKTI response, and cytokine responses, will also be analysed. Azitra anticipates releasing interim safety data in early 2025, with full results expected in the latter half of the year. ATR-12 is Azitra leading candidate and a specially engineered strain of Staphylococcus epidermidis designed to deliver therapeutic levels of a LEKTI protein subunit to combat Netherton syndrome, a serious genetic skin condition. Azitra CEO Francisco Salva said: “Dosing the first
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AZTR
News
- AZTR: Planning 2nd Site for ATR-12 Trial [Yahoo! Finance]Yahoo! Finance
- Azitra, Inc. Announces Q3 2024 Financial Results and Provides Business Updates [Yahoo! Finance]Yahoo! Finance
- Azitra, Inc. Announces Q3 2024 Financial Results and Provides Business UpdatesPR Newswire
- Azitra to Present at BIO-Europe 2024Business Wire
- Azitra to Participate in the 2024 Maxim Healthcare Virtual SummitBusiness Wire
AZTR
Sec Filings
- 11/14/24 - Form SC
- 11/14/24 - Form SC
- 11/13/24 - Form 8-K
- AZTR's page on the SEC website