Resolution scores $83m to develop macrophage cell therapies [Yahoo! Finance]
AstraZeneca PLC - American Depositary Shares (AZN)
Last astrazeneca plc - american depositary shares earnings: 2/5 04:00 pm
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Source: Yahoo! Finance
The UK-based company plans to use the money to finance the Phase I/II EMERALD trial for its lead candidate, RTX001, as a treatment for end-stage liver disease. Resolution also intends to direct the funds to expand its pipeline in other inflammatory and fibrotic indications, including graft-vs-host disease (GvHD) and lung fibrosis. RTX001 is an engineered autologous macrophage cell therapy. Macrophages act as effector cells of the innate immune system and play an important role in mediating inflammation and eliminating foreign organisms. RTX001 is designed to decrease fibrosis and inflammation in patients with end-stage liver disease. The open-label Phase I/II EMERALD trial will evaluate the therapy in the indication, with recruitment expected to start across the UK and Spain by the end of the year. The trial's primary endpoint will measure clinical events including all-cause mortality. Resolution previously raised £22m in Series A funding in 2020. Both financing rounds were led
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AZN
Sec Filings
- 10/1/24 - Form 6-K
- 9/26/24 - Form 6-K
- 9/23/24 - Form 6-K
- AZN's page on the SEC website