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-0.000126318448809513 -0.00056843301964254 -0.000252636897618847 0.000505273795237694 -0.000442114570833027 0.00214741362976065 0.00404219036190227 0.00486326027916366
Stock impact report

China Approves AstraZeneca's Tagrisso-Chemotherapy Combo Regime For Previously Untreated Lung Cancer Patients [Yahoo! Finance]

AstraZeneca PLC - American Depositary Shares (AZN) 
Last astrazeneca plc - american depositary shares earnings: 2/5 04:00 pm Check Earnings Report
US:NYSE Investor Relations: astrazeneca.com/investor-relations.html
Company Research Source: Yahoo! Finance
for the 1st-line treatment of adult patients with locally advanced or metastatic epidermal growth factor receptor-mutated non-small cell lung cancer whose tumors have exon 19 deletions or exon 21 mutations. On Tuesday, the Tagrisso with pemetrexed and platinum-based chemotherapy regime received approval in Japan for the same indication. China's National Medical Products Administration approved the drug based on the results of the FLAURA2 Phase 3 trial, which were published in the New England Journal of Medicine In the overall trial population, Tagrisso, with the addition of chemotherapy, reduced the risk of disease progression or death by 38% by investigator assessment compared to Tagrisso monotherapy, which is the 1st-line global standard of care. Median progression-free survival (PFS) was 25.5 months for patients treated with Tagrisso plus chemotherapy, an 8.8-month improvement versus Tagrisso monotherapy (16.7 months). PFS results by blinded independent central review (BI Show less Read more
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