AstraZeneca's Truqap flops in Phase III triple negative breast cancer trial [Yahoo! Finance]
AstraZeneca PLC - American Depositary Shares (AZN)
Last astrazeneca plc - american depositary shares earnings: 2/5 04:00 pm
Check Earnings Report
US:NYSE Investor Relations:
astrazeneca.com/investor-relations.html
Company Research
Source: Yahoo! Finance
The Truqap and chemotherapy (paclitaxel) combo in the Phase III CAPItello-290 trial failed to meet its dual primary endpoints of improvement in overall survival (OS) versus chemotherapy and placebo in either the overall trial population or in a subgroup of patients that had tumours with specific biomarker alterations (PIK3CA, AKT1 or PTEN). According to research, mutations in PIK3CA, AKT1 and alterations in PTEN affect approximately 35% of patients with TNBC. The Phase III, double-blind, randomised trial (NCT03997123) evaluated the efficacy of Truqap in combination with chemotherapy in patients with locally advanced (inoperable) or metastatic TNBC. The safety profile of Truqap in combination with paclitaxel in CAPItello-290 was broadly consistent with the known safety profile of each medicine. AstraZeneca's executive vice president for oncology R&D, Susan Galbraith, said: “While we are disappointed in the CAPItello-290 outcome, these results will further our understanding of
Show less
Read more
Impact Snapshot
Event Time:
AZN
Last Price
Price Change
Price Change%
Volume Shares
Max Up
Max Down
%
Volume Ratio
Performance Comparison
Updated
|
Event Day
Stock performance from the time of news release until the following 4pm ET market close
|
Last price at news event
|
Since Event
Multi-day stock performance from the time of the news release
|
|---|---|---|
|
EVENT DAY
Stock performance from the time of news release until the following 4pm ET market close
|
LAST
PRICE AT NEWS EVENT |
SINCE EVENT
Multi-day stock performance from the time of the news release
|
| Last Price | ||
| VWAP | ||
|
High:
|
Max Up |
High:
|
|
Low:
|
Max Down |
Low:
|
|
%
|
Post news range |
%
|
|
|
Price change |
|
|
|
Price Change Percentage |
|
|
|
S&P 500 (SPX) |
|
|
%
|
Volume ratio |
%
|
| Volume | ||
| Ticks | ||
|
|
Avg transaction size |
|
Don't Miss Out On The Next BIG Stock Move
Event day
Event Day Chart will not be displayed beyond 90-day period of the event
Performance since event
Time And Velocity Analysis
Be the first to know
Opt in for alerts from News Quantifed
Sign Up Today
Opt-in for
AZN alerts
Learn More With NQ
Reading the Impact Report
Help Me Understand This Data
Help Me Understand This Data
How NQ Works
What is news-based trading?
And why is it so successful?
And why is it so successful?
Movers & Shakers
The biggest gainers and losers and WHY it moved
AZN alerts
High impacting AstraZeneca PLC - American Depositary Shares news events
Weekly update
A roundup of the hottest topics
AZN
News
- US' first self-administered flu vaccine could increase accessibility and uptake [Yahoo! Finance]Yahoo! Finance
- AstraZeneca's Tagrisso gains FDA approval for stage III NSCLC [Yahoo! Finance]Yahoo! Finance
- AstraZeneca Stock Up Almost 14% in 6 Months: Time to Buy? [Yahoo! Finance]Yahoo! Finance
- AZN's Tagrisso Gets FDA Nod for Expanded Use in NSCLC [Yahoo! Finance]Yahoo! Finance
- AstraZeneca's Top-Selling Cancer Drug Tagrisso Receives FDA Green Light For Another Lung Cancer Indication [Yahoo! Finance]Yahoo! Finance
AZN
Sec Filings
- 9/26/24 - Form 6-K
- 9/23/24 - Form 6-K
- 9/23/24 - Form 6-K
- AZN's page on the SEC website