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-5.36638344087053E-05 -0.000127771034306407 0.000127771034306588 6.38855171533848E-05 -0.00121382482591195 -0.00198045103175112 -0.00146936689452495 -0.000811346067846299
Stock impact report

AstraZeneca's Top-Selling Cancer Drug Tagrisso Receives FDA Green Light For Another Lung Cancer Indication [Yahoo! Finance]

AstraZeneca PLC - American Depositary Shares (AZN) 
Last astrazeneca plc - american depositary shares earnings: 2/5 04:00 pm Check Earnings Report
US:NYSE Investor Relations: astrazeneca.com/investor-relations.html
Company Research Source: Yahoo! Finance
Tagrisso is indicated for patients with exon 19 deletions or exon 21 (L858R) mutations. Tagrisso is AstraZeneca's top-selling cancer drug, and in the second quarter of 2024, it generated around $1.6 billion in sales The approval follows the FDA's Priority Review based on results from the LAURA Phase 3 trial. Tagrisso reduced the risk of disease progression or death by 84% compared to placebo. Median progression-free survival (PFS) was 39.1 months in patients treated with Tagrisso versus 5.6 months for placebo. Overall survival (OS) results remain immature at this current analysis. The trial continues to assess OS as a secondary endpoint. Each year in the US, there are more than 200,000 people diagnosed with lung cancer, and 80-85% of these patients are diagnosed with NSCLC, the most common form of lung cancer. Approximately 15% of NSCLC patients in the US have EGFR mutations. Nearly one in five people diagnosed with NSCLC has an unresectable tumor. The safety and tole Show less Read more
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