Arcus and AstraZeneca enter trial collaboration for renal cancer treatment [Yahoo! Finance]
AstraZeneca PLC - American Depositary Shares (AZN)
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Source: Yahoo! Finance
the combination of casdatifan (AB521) and volrustomig in patients with clear cell renal cell carcinoma (ccRCC). Casdatifan is an investigational HIF-2a inhibitor of Arcus while volrustomig is AstraZeneca's investigational PD-1/CTLA-4 bispecific antibody. AstraZeneca will sponsor and operationalise the trial as per the agreed deal. This study aims to assess the safety and early efficacy of the combination therapy in patients with advanced ccRCC. Arcus CEO Terry Rosen said: “We believe casdatifan has best-in-class potential, based on the observed PK and PD profiles and the emerging clinical data from our ARC-20 study in patients with ccRCC. “This agreement will enable Arcus and AstraZeneca to collaborate and assess the potential for the novel combination of casdatifan with volrustomig to improve outcomes for patients with ccRCC.” This new development is said to be the second clinical collaboration between the two companies, following their 2020 announcement of a partnership
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- 10/1/24 - Form 6-K
- 9/26/24 - Form 6-K
- 9/23/24 - Form 6-K
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