AstraZeneca & Aptamer partner to bolster targeted siRNA therapies [Yahoo! Finance]
AstraZeneca PLC - American Depositary Shares (AZN)
Last astrazeneca plc - american depositary shares earnings: 2/5 04:00 pm
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Source: Yahoo! Finance
The companies did not disclose the financials behind the collaboration but following the 3 July announcement, Aptamer's shares were up by 18% to $0.95 (£0.74). The collaboration between the two UK-based companies will begin in pre-clinical stages, starting with lab data, before moving to animal studies. The Optimer system has already shown to be effective in fibrotic liver in in-vitro studies. The companies would not confirm which indication they will be investigating at pre-clinical stages. While the more known and investigated messenger RNA (mRNA), used to develop the Covid-19 vaccinations, carries genetic information for protein synthesis, siRNA targets and silences specific genes with precision. A huge challenge that has faced drug developers however is off-target effects, where the siRNA may bind to unintended mRNA targets, leading to unintended gene silencing. As a result, a more effective delivery system would be hugely beneficial. Aptamer claims that its Optimer tec
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Sec Filings
- 10/1/24 - Form 6-K
- 9/26/24 - Form 6-K
- 9/23/24 - Form 6-K
- AZN's page on the SEC website