Alexion, AstraZeneca Rare Disease reaches an agreement with the pan-Canadian Pharmaceutical Alliance (pCPA) for Koselugo (selumetinib) for the treatment of paediatric patients with neurofi...
AstraZeneca PLC - American Depositary Shares (AZN)
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MISSISSAUGA, ON Dec. 18, 2024 /CNW/ - Alexion Pharma Canada Corp., AstraZeneca's Rare Disease group, has entered into a Letter of Intent (LOI) with the pan-Canadian Pharmaceutical Alliance (pCPA) for Koselugo for the treatment of paediatric patients aged two years and above with neurofibromatosis type 1 (NF1) who have symptomatic, inoperable plexiform neurofibromas (PN). With the agreement in place with the pCPA, individual provinces and territories may now initiate the process to list Koselugo on their formularies, the timing of which will vary by province and territory. Following the agreement, the Province of Quebec was the first to list Koselugo and provide public reimbursement of the only approved therapy for eligible children living with NF1 PN. NF1 is a rare, progressive genetic condition affecting one in 3,000 individuals worldwide, most commonly diagnosed in children under the age of 10. In 30-50% of patients, tumours develop on the nerve sheaths (plexiform neurofibromas)
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