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0.000227551995630924 9.10207982523179E-05 -0.00177490556592188 4.55103991261589E-05 -0.00332225913621271 0.000227551995630924 0.00213898875893141 0.00914759022436623
Stock impact report

Why Shares of Axsome Therapeutics Slumped Today [Yahoo! Finance]

Axsome Therapeutics, Inc. (AXSM) 
Last axsome therapeutics, inc. earnings: 3/12 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: axsome.com
Company Research Source: Yahoo! Finance
The slump comes after the company announced the results of a phase 3 trial of solriamfetol (brand name Sunosi) in major depressive disorder (MDD). The trial was somewhat complicated, so bear with me. It was a six-week proof-of-concept phase 3 trial for MDD "with and without severe excess daytime sleepiness (EDS)." The primary aim of the trial was to demonstrate significant improvement in the overall population (consisting of 51 patients with severe EDS and 295 without severe EDS) using solriamfetol. The degree of severity of EDS was assessed with the Epworth Sleepiness Scale (ESS), and the trial used the Montgomery-Asberg Depression Rating Scale (MADRS). The details: The trial did not demonstrate a statistical improvement in the overall population when comparing patients on solriamfetol to those on a placebo. In the MDD patients with severe EDS, the use of solriamfetol "resulted in clinically meaningful and numerically greater improvements compared to placebo on multiple eff Show less Read more
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