Anavex Life Sciences Presented at the 6th Annual European Rett Syndrome Conference Preliminary Clinical Efficacy Data from the U.S. Rett Syndrome Phase 2 ANAVEX®2-73 Study
Anavex Life Sciences Corp. (AVXL)
NASDAQ:AMEX Investor Relations:
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Source: GlobeNewswire
NEW YORK, Sept. 27, 2019 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental disorders including Alzheimer’s disease, Parkinson’s disease, Rett syndrome and other central nervous system (CNS) disorders, today presented preliminary clinical efficacy data from the PK cohort (Part A) of the U.S. Phase 2 Rett syndrome clinical trial ANAVEX®2-73-RS-001. “The data from the PK cohort (Part A, n=6) is very encouraging because of the (1) magnitude of change (large to very large effect sizes: Cohen’s d: RSBQ Total 1.47; Cohen’s d: Glutamate 1.11), (2) the efficacy signal on both caregiver- and clinician-based measures of severity and correlations with key biomarker related to disease pathogenesis (Glutamate), (3) the short duration of treatment with ANAVEX®2-73 (blarcamesine), (4) the relatively low dose, (5) th
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