Aurinia doses first subject in Phase Ia trial of AUR200 for autoimmune diseases [Yahoo! Finance]
Aurinia Pharmaceuticals Inc - Common Shares (AUPH)
Last aurinia pharmaceuticals inc - common shares earnings: 3/5 04:02 pm
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Source: Yahoo! Finance
The trial is designed to evaluate the safety, tolerability, pharmacokinetics, and biomarker changes of AUR200 in healthy volunteers. Results from the study are expected in the first half of next year, the company said. AUR200 is an IgG4 Fc-fusion protein claimed to have minimal effector function. It targets both B-cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL), crucial cytokines in B-cell survival, and differentiation regulation. The B-cell maturation antigen (BCMA) domain of AUR200 allows for enhanced binding to BAFF and APRIL. Dual inhibition of these cytokines is said to be a clinically validated mechanism with significant therapeutic potential for various autoimmune diseases. The company plans to develop AUR200 for disease states with limited current market options, including a larger indication and a faster-to-market smaller indication that aligns with the FDA criteria for rare and orphan diseases. Specific indications and development pla
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News
- Aurinia Commends 2024 Updated ACR Guidelines for Screening, Treatment, and Management of Lupus Nephritis [Yahoo! Finance]Yahoo! Finance
- Aurinia Commends 2024 Updated ACR Guidelines for Screening, Treatment, and Management of Lupus NephritisBusiness Wire
- Aurinia Presents New Data Underscoring Critical Importance of Earlier Lupus Nephritis Detection and Intervention and Value of LUPKYNIS® in Managing LN at American College of Rheumatology Convergence 2024Business Wire
- Aurinia to Participate in Jefferies London Healthcare Conference [Yahoo! Finance]Yahoo! Finance
- Aurinia to Participate in Jefferies London Healthcare ConferenceBusiness Wire
AUPH
Earnings
- 11/7/24 - Beat
AUPH
Sec Filings
- 11/14/24 - Form SC
- 11/12/24 - Form 4
- 11/12/24 - Form 4
- AUPH's page on the SEC website