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Stock impact report

Arrowhead Pharmaceuticals seeks approval for obesity treatment trial in New Zealand [Yahoo! Finance]

Arrowhead Pharmaceuticals, Inc. (ARWR) 
Last arrowhead pharmaceuticals, inc. earnings: 2/5 04:00 pm Check Earnings Report
US:NASDAQ Investor Relations: ir.arrowheadpharma.com/investor-relations
Company Research Source: Yahoo! Finance
Phase I/IIa clinical trial of ARO-INHBE, an investigational RNA interference (RNAi) therapy for treating obesity, in New Zealand. The company's application was submitted to the New Zealand Medicines and Medical Devices Safety Authority and will be reviewed by the Standing Committee on Therapeutic Trials. The AROINHBE-1001 dose-escalation study is designed to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of ARO-INHBE. It will involve up to 78 adult diabetic and non-diabetic subjects with obesity. In the trial's first portion, single and multiple doses of ARO-INHBE will be assessed as a standalone treatment, while the second portion will evaluate its combination with tirzepatide. Tirzepatide is a medication currently approved for managing type 2 diabetes (T2D) and weight control. ARO-INHBE is designed to suppress the expression of the INHBE gene in the liver, which in turn reduces the secretion of Activin E, a gene product involved in regulating ener Show less Read more
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