FDA grants breakthrough therapy status to Arrowhead's plozasiran [Yahoo! Finance]
Arrowhead Pharmaceuticals, Inc. (ARWR)
Last arrowhead pharmaceuticals, inc. earnings: 2/5 04:00 pm
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Source: Yahoo! Finance
Plozasiran is intended for use as an adjunct to diet to cut down triglycerides in adults with familial chylomicronemia syndrome (FCS), a rare genetic disease. The designation speeds up the development and review of drugs for serious conditions, where initial clinical evidence suggests significant improvement over existing treatments. Plozasiran reduces the production of apolipoprotein C-III (APOC3), a key regulator of triglyceride metabolism. High levels of APOC3 can lead to increased triglyceride levels in the blood, a characteristic of FCS. In clinical studies, plozasiran has shown promising results by reducing triglycerides and other atherogenic lipoproteins in patients with FCS, severe hypertriglyceridemia (SHTG) and mixed hyperlipidaemia. The safety profile of plozasiran was also found to be favourable, with treatment-emergent adverse events generally reflecting the comorbidities and underlying conditions of the study populations. The SUMMIT programme, which includes
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News
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ARWR
Earnings
- 8/8/24 - Miss
ARWR
Sec Filings
- 8/8/24 - Form 8-K
- 8/8/24 - Form 10-Q
- 7/3/24 - Form 4
- ARWR's page on the SEC website