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Stock impact report

Annexon (ANNX) Up as Phase III Neuro Disorder Study Meets Goals [Yahoo! Finance]

Annexon, Inc. - common stock (ANNX) 
Company Research Source: Yahoo! Finance
candidate, ANX005, a monoclonal antibody, in patients with Guillain-Barré syndrome (GBS). Per the data readout from the pivotal phase III study, treatment with a single infusion of the 30 mg/kg dose strength of ANX005 met the study's primary endpoint, achieving a highly statistically significant 2.4-fold improvement on the GBS-disability scale (GBS-DS) at week 8. Treatment with ANX005 30 mg/kg also showed improvement in key secondary endpoints compared with placebo, which includes early gains in muscle strength as measured by the Medical Research Council sum score at day 8 and week 8 and a median of 28 fewer days on artificial ventilation through week 26. Furthermore, a 31-day reduction in the median time to walk independently compared with placebo was also observed upon treatment with the candidate's 30 mg/kg dose in a prespecified analysis. Annexon stated that patients treated with ANX005 30 mg/kg showed signs of improvement sooner compared with placebo on all the above-ment Show less Read more
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