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Stock impact report

One dose of experimental drug nearly wipes out stealthy cholesterol in 'remarkable' trial [MSNBC.com]

Amgen Inc. (AMGN) 
Last amgen inc. earnings: 4/30 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: investors.amgen.com
Company Research Source: MSNBC.com
A single dose of an experimental drug dramatically reduced levels of a deadly form of cholesterol, often thought to be untreatable, for up to one year.Lipoprotein(a) is a type of cholesterolThe findings, cardiologists say, are a critical step toward treating the millions of Americans genetically predisposed to abnormally high levels of lipoprotein(a), or Lp(a).“It’s remarkable,” said Dr. Eric Brandt, director of preventive cardiology at the University of Michigan Frankel Cardiovascular Center in Ann Arbor, who wasn’t involved with the new research. “These drugs have the potential to nearly eliminate that lipoprotein.”People with high levels of Lp(a) — some 64 million adults in the U.S. — are at extremely high risk ofcholesterol buildupFindings from anearlier trialThe latest study, a Phase 2 clinical trial funded by Lilly, included 320 people. One injection, researchers found, cut Lp(a) levels by 93.9% after six months. After a year, the effects waned, but only slightly, with levels m Show less Read more
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