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-0.023121387283237 -0.0173410404624278 -0.023121387283237 -0.00578034682080925 -0.0202312138728323 -0.0346820809248554 -0.0231213872832369 -0.0751445086705202
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EXCLUSIVE: Alzamend Neuro Reveals Full Data Set From Multiple Ascending Dose Trial For Lead Candidate For Dementia Related to Alzheimer's [Yahoo! Finance]

Alzamend Neuro, Inc. (ALZN) 
Company Research Source: Yahoo! Finance
data set from its multiple ascending dose clinical trial for AL001 for dementia related to Alzheimer's. Preliminary results were released in June 2023 Identified by an independent safety review committee, this MTD represents a pivotal step forward; it delivers lithium at a lithium carbonate equivalent dose of 240 mg, taken three times daily (TID). The Phase 2A study evaluated the safety and tolerability of AL001 under multiple-dose, steady-state conditions. It determined the MTD in patients diagnosed with mild to moderate Alzheimer's disease and in healthy non-elderly and elderly subjects with adequate renal function. Lithium has been well characterized for safety and is approved and marketed in multiple formulations for bipolar disorder. The safety profile was demonstrated to be benign at all dose levels. The dose level chosen for further development was based on avoiding plasma drug concentrations associated in the medical literature with exceeding the upper limit of the t Show less Read more
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