ALX Oncology Announces First Patients Dosed with Evorpacept and Sarclisa As Part of Randomized Phase 1/2 UMBRELLA Study with Sanofi
ALX Oncology Holdings Inc. (ALXO)
Company Research
Source: GlobeNewswire
SOUTH SAN FRANCISCO, Calif., Sept. 04, 2024 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., (“ALX Oncology” or “the Company”) (Nasdaq: ALXO), an immuno-oncology company developing therapies that block the CD47 immune checkpoint pathway, announced the first patients have been dosed in an arm of the randomized UMBRELLA phase 1/2 clinical study partnered with Sanofi that is evaluating evorpacept in combination with SARCLISA® (isatuximab-irfc). Evorpacept is ALX Oncology’s investigational CD47-blocking therapeutic that uniquely combines a high-affinity CD47-binding domain with an inactivated Fc domain and SARCLISA is Sanofi’s approved CD38 monoclonal antibody in patients with relapsed or refractory multiple myeloma (RRMM). SARCLISA binds to a specific epitope on the CD38 receptor on multiple myeloma (MM) cells, inducing distinct antitumor activity. CD38 is highly and uniformly expressed on the surface of MM cells and after first-line treatment, some relapsed or recurred patients have s
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ALXO
News
- Bluejay Therapeutics Announces Expansion of Leadership Team and Board of Directors [Yahoo! Finance]Yahoo! Finance
- ALX Oncology Appoints Alan Sandler, M.D., as Chief Medical Officer [Yahoo! Finance]Yahoo! Finance
- ALX Oncology Appoints Alan Sandler, M.D., as Chief Medical OfficerGlobeNewswire
- ALX Oncology Holdings Inc. (NASDAQ: ALXO) had its "overweight" rating re-affirmed by analysts at Cantor Fitzgerald.MarketBeat
- ALX Oncology Reports Third Quarter 2024 Financial Results and Provides Corporate UpdateGlobeNewswire
ALXO
Earnings
- 11/7/24 - Beat
ALXO
Sec Filings
- 11/19/24 - Form 4
- 11/14/24 - Form SC
- 11/14/24 - Form SC
- ALXO's page on the SEC website