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Stock impact report

ALEC Stock Tanks as Alzheimer's Drug Fails in Mid-Stage Study [Yahoo! Finance]

Alector, Inc. (ALEC) 
Last alector, inc. earnings: 3/24 04:05 pm Check Earnings Report
Company Research Source: Yahoo! Finance
The phase II INVOKE-2 study evaluated the safety and efficacy of AL002 in slowing disease progression in individuals with early AD. The study's primary endpoint was to check disease progression, as measured by the Clinical Dementia Rating Sum of Boxes (“CDR-SB”) scale. The CDR-SB is a numerical scale that measures the severity of the AD indication. In the study, treatment with AL002 failed to meet the primary endpoint of slowing Alzheimer's clinical progression as measured by the CDR-SB. Also, no treatment effects favored AL002 on secondary clinical and functional endpoints in the INVOKE-2 study. The stock hit its 52-week low on the pipeline setback. Year to date, shares of Alector have plunged 67.8% compared with the industry's 7.8% decline. Image Source: Zacks Investment Research Data from the INVOKE-2 study demonstrated no significant effects on Alzheimer's fluid biomarkers favoring AL002, as well as amyloid PET imaging showed no treatment-related reduction of brain amyloi Show less Read more
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