Alector Announces Results from AL002 INVOKE-2 Phase 2 Trial in Individuals with Early Alzheimer’s Disease and Provides Business Update
Alector, Inc. (ALEC)
Last alector, inc. earnings: 3/24 04:05 pm
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Source: GlobeNewswire
SOUTH SAN FRANCISCO, Calif., Nov. 25, 2024 (GLOBE NEWSWIRE) -- Alector, Inc. (Nasdaq: ALEC), a clinical-stage biotechnology company pioneering novel, genetically validated therapies for the treatment of neurodegenerative diseases, today announced results from the INVOKE-2 Phase 2 clinical trial evaluating the safety and efficacy of AL002 in slowing disease progression in individuals with early Alzheimer’s disease (AD). Treatment with AL002 resulted in sustained target engagement and pharmacodynamic responses indicative of microglial activation. However, AL002 failed to meet the primary endpoint of slowing of Alzheimer’s clinical progression as measured by the Clinical Dementia Rating Sum of Boxes (CDR®-SB), and there were no treatment effects that favored AL002 on secondary clinical and functional endpoints. Similarly, there were no significant effects on Alzheimer’s fluid biomarkers favoring AL002, and amyloid PET imaging demonstrated no treatment-related reduction of brain amyloid
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- Alector, Inc. (NASDAQ: ALEC) was downgraded by analysts at Mizuho from an "outperform" rating to a "neutral" rating. They now have a $2.50 price target on the stock, down previously from $9.00.MarketBeat
- Alector, Inc. (NASDAQ: ALEC) was downgraded by analysts at Stifel Nicolaus from a "buy" rating to a "hold" rating. They now have a $4.00 price target on the stock.MarketBeat
- Alector, Inc. (NASDAQ: ALEC) was downgraded by analysts at Bank of America Co. from a "neutral" rating to an "underperform" rating. They now have a $1.00 price target on the stock, down previously from $9.00.MarketBeat
- Alector, Inc. (NASDAQ: ALEC) had its price target lowered by analysts at HC Wainwright from $35.00 to $7.00. They now have a "buy" rating on the stock.MarketBeat
- ALEC Stock Tanks as Alzheimer's Drug Fails in Mid-Stage Study [Yahoo! Finance]Yahoo! Finance
ALEC
Earnings
- 11/6/24 - Beat
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Sec Filings
- 12/6/24 - Form SC
- 12/3/24 - Form 4
- 12/3/24 - Form 4
- ALEC's page on the SEC website