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0 -0.000112854079674878 0.00620697438212404 0.00575555806342405 0.00801263965692369 0.00710980701952387 0.0159124252341723 0.00665839070082387
Stock impact report

Agios Pharmaceuticals' Rare Blood Disorder Drug Misses Primary Goal In Pediatric Study, Stock Slides [Yahoo! Finance]

Agios Pharmaceuticals, Inc. (AGIO) 
Last agios pharmaceuticals, inc. earnings: 4/30 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: investor.agios.com/investor-overview
Company Research Source: Yahoo! Finance
Pyruvate kinase deficiency is a rare genetic disorder characterized by the premature destruction of red blood cells. Using Bayesian methodology, the prespecified statistical criterion for the primary endpoint in ACTIVATE-KidsT was not met using low or moderate borrowing of data from the ACTIVATE-T study in adults. Also Read: Why Is Agios Pharmaceuticals Stock Trading Higher On Monday In the ACTIVATE-KidsT study, 28.1% of patients in the mitapivat arm achieved the primary endpoint of transfusion reduction response, compared to 11.8% of patients in the placebo arm. Transfusion-free response and normal hemoglobin response were secondary endpoints in this study and were only observed in patients in the mitapivat arm. Mitapivat was generally safe and well-tolerated, with safety results consistent with the safety profile for mitapivat previously observed in adults with PK deficiency who are regularly transfused. Six patients (18.8%) in the mitapivat arm compared to 0 in the pla Show less Read more
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