Acurx Announces Publication of Nonclinical In Vivo Data Differentiating Ibezapolstat's Gut Microbiome Effects from Other Anti-CDI Antibiotics
Acurx Pharmaceuticals, Inc. (ACXP)
Company Research
Source: PR Newswire
First ever head-to-head comparison of gut microbiome changes associated with ibezapolstat (IBZ) to other anti-CDI antibiotics in a germ-free mouse modelChanges in alpha and beta microbiome diversities following IBZ treatment were less pronounced compared to those observed in vancomycin (VAN)-or metronidazole (MET)-treated groups, complementing prior Phase 2 clinical findings showing IBZ's more selective antibacterial activityNotable differences were observed between the microbiome of IBZ- and fidaxomicin (FDX)-treated groups, which may allow for differentiation of these two anti-CDI antibiotics in future studiesResults establish IBZ differentiating effects on the gut microbiome, indicating a more selective spectrum of microbiome alteration compared to broader-spectrum antibiotics like VAN and MET and a narrower spectrum of microbiome alteration compared to FDXPreparation continues to advance IBZ into international Ph3 clinical trials for treatment of CDIIBZ has previously been granted
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News
- Acurx Pharmaceuticals (NASDAQ:ACXP) was upgraded by analysts at <a style="font-weight:bold" href="https://www.wallstreetzen.com/newsletters/zen-ratings?ticker=ACXP&utm_campaign=getratings&utm_medium=online&utm_source=MarketBeat">Wall StrMarketBeat
- Health~Holland Awards Another Innovative Research Grant for DNA Pol IIIC Inhibitors to Leiden University Medical Center and Acurx PharmaceuticalsPR Newswire
- New to The Street Airs Landmark Show #700 Today at 6:30 PM ET on Bloomberg Television [Yahoo! Finance]Yahoo! Finance
- Acurx Pharmaceuticals GAAP EPS of -$1.23 beats by $0.05 [Seeking Alpha]Seeking Alpha
- Acurx Pharmaceuticals, Inc. Reports Third Quarter Results and Provides Business UpdatePR Newswire
ACXP
Earnings
- 11/12/25 - Beat
ACXP
Analyst Actions
- 9/30/25 - HC Wainwright
ACXP
Sec Filings
- 11/14/25 - Form SCHEDULE
- 11/12/25 - Form 10-Q
- 11/10/25 - Form 424B3
- ACXP's page on the SEC website