Aclaris doses first subject in Phase IIa atopic dermatitis treatment trial [Yahoo! Finance]
Aclaris Therapeutics, Inc. (ACRS)
Last aclaris therapeutics, inc. earnings: 2/25 04:01 pm
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Source: Yahoo! Finance
The open-label trial aims to assess the safety, tolerability, pharmacokinetics, and efficacy of ATI-2138 in AD patients over 12 weeks. Being conducted in the US, the trial plans to enrol approximately 15 subjects. Its primary endpoints focus on safety parameters while the secondary endpoints measure efficacy through Eczema Area and Severity Index (EASI) responses, including EASI-50; EASI-75; and EASI-90, as well as Validated Investigator Global Assessment (vIGA) responses; body surface area (BSA) responses; and other relevant measures. Topline data from this trial is anticipated in the first half of next year. ATI-2138 is an investigational oral covalent interleukin-2-inducible T-cell kinase (ITK) and Janus kinase (JAK) 3 inhibitor. The asset is being developed as a potential treatment for T-cell-mediated autoimmune diseases by disrupting T-cell signalling through the inhibition of ITK/JAK3 pathways in lymphocytes. Aclaris Therapeutics is dedicated to creating new treatme
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ACRS
News
- Aclaris Therapeutics Reports Third Quarter 2024 Financial Results and Provides a Corporate UpdateGlobeNewswire
- Aclaris Therapeutics, Inc. (NASDAQ: ACRS) had its "neutral" rating re-affirmed by analysts at HC Wainwright.MarketBeat
- Aclaris Therapeutics Announces First Patient Dosed in Phase 2a Clinical Trial of ATI-2138, an Investigational Oral Covalent ITK/JAK3 Inhibitor for the Treatment of Moderate to Severe Atopic DermatitisGlobeNewswire
- Aclaris Therapeutics to Participate in the 2024 Cantor Global Healthcare ConferenceGlobeNewswire
- Aclaris Therapeutics, Inc. (NASDAQ: ACRS) had its "neutral" rating re-affirmed by analysts at HC Wainwright.MarketBeat
ACRS
Earnings
- 11/6/24 - Miss
ACRS
Sec Filings
- 11/6/24 - Form 10-Q
- 11/6/24 - Form 8-K
- 11/5/24 - Form 4
- ACRS's page on the SEC website