Aclaris Therapeutics Announces Positive Results From Phase 1 Single and Multiple Ascending Dose Trial of ATI-450, an Investigational Oral MK2 Inhibitor
Aclaris Therapeutics, Inc. (ACRS)
Last aclaris therapeutics, inc. earnings: 2/25 04:01 pm
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Source: GlobeNewswire
• Oral small molecule showed marked inhibition of TNFa, IL1ß, IL8, and IL6• Preliminary data support progression to Phase 2a Proof of Concept Trials in Immuno-Inflammatory Diseases WAYNE, Pa., Jan. 09, 2020 (GLOBE NEWSWIRE) -- Aclaris Therapeutics, Inc. (NASDAQ: ACRS), a physician-led biopharmaceutical company focused on immuno-inflammatory diseases, today announced positive results from ATI-450-PKPD-101, a Single Ascending Dose and Multiple Ascending Dose (SAD/MAD) Phase 1 clinical trial of the investigational compound ATI-450. Preliminary data demonstrated that ATI-450: resulted in marked inhibition of TNFa, IL1ß, IL8, and IL6;was generally well-tolerated at all doses tested in the trial;had dose proportional pharmacokinetics (PK) with a terminal half-life of 9-12 hours; andhad no meaningful food effect or drug-drug interaction (DDI) with methotrexate. ATI-450-PKPD-101 was a first-in-human, randomized, observer-blind, placebo-controlled Phase 1 clinical trial desi
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News
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- Aclaris Therapeutics, Inc. (NASDAQ: ACRS) was upgraded by analysts at Leerink Partnrs from a "hold" rating to a "strong-buy" rating.MarketBeat
- Aclaris Stock Soars As Analysts See Fresh Momentum After Strategic Review And Encouraging Promising Pipeline Developments [Yahoo! Finance]Yahoo! Finance
- ACRS Stock Up on Licensing Deal With Biosion for Two Immunology Drugs [Yahoo! Finance]Yahoo! Finance
ACRS
Earnings
- 11/6/24 - Miss
ACRS
Sec Filings
- 11/21/24 - Form SC
- 11/20/24 - Form 4
- 11/18/24 - Form 3
- ACRS's page on the SEC website