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Stock impact report

FDA grants IND clearance for Adicet Bio's renal cell carcinoma treatment trial [Yahoo! Finance]

Adicet Bio, Inc. (ACET) 
Last adicet bio, inc. earnings: 5/3 05:00 pm Check Earnings Report
US:NASDAQ Investor Relations: aceto.com/ir/index.html
Company Research Source: Yahoo! Finance
a Phase I clinical trial of ADI-270 for relapsed or refractory renal cell carcinoma (r/r RCC). ADI-270 is an armoured allogeneic 'off-the-shelf' gamma delta chimeric antigen receptor (CAR) T-cell therapy candidate that is designed to treat CD70+ cancers. The prospective, multicentre, open-label trial is set to begin in the second half of this year to evaluate the drug's safety and anti-tumour activity in adults with clear cell r/r RCC. Following lymphodepletion, participants will be given a single dose of ADI-270 with 3E8 CAR-positive cells, with the potential for a second dose based on specific criteria outlined in the study protocol. The trial will have dose escalation and expansion phases to assess the therapy's safety, tolerability and pharmacokinetics. It will also measure anti-tumour activity using metrics such as overall response rate, duration of response and disease control rate. Adicet Bio president and CEO Chen Schor said: “ADI-270 is the first ever gamma delta Show less Read more
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