AbbVie reports final analysis from Phase III trial of Elahere for ovarian cancer [Yahoo! Finance]
AbbVie Inc. (ABBV)
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Source: Yahoo! Finance
conjugate (ADC) Elahere against chemotherapy for treating platinum-resistant ovarian cancer (PROC). The randomised trial assessed the therapy's safety and efficacy when given to women with folate receptor alpha (FRa) positive PROC. Its primary endpoint was progression-free survival (PFS), with its secondary endpoints being objective response rate (ORR) and overall survival (OS). The study enrolled 453 subjects who had received up to three previous therapies and exhibited high-grade serous epithelial PROC expressing high FRa levels. The median follow-up of 30.5 months showed that ADC treatment led to a median PFS of 5.59 months compared to 3.98 months for investigator's choice (IC) chemotherapy, decreasing the tumour progression or mortality risk by 37%. In addition, it achieved an ORR of 41.9%, significantly higher than the 15.9% achieved with chemotherapy. Subjects treated with Elahere also experienced a superior median OS of 16.85 months against 13.34 months for those re
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ABBV
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- 10/31/25 - Beat
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- 11/20/25 - Form F-6
- 11/4/25 - Form 10-Q
- 10/31/25 - Form 8-K
- ABBV's page on the SEC website