News Quantified

IPSEY – ipsen sa s/adr (US:NASDAQ)

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Bylvay® (odevixibat) data shows sustained improvement in severe itch and serum bile acid levels in patients with PFIC and ALGS

Iqirvo® (elafibranor) data shows efficacy and safety for up to 3 years in patients with PBC with improvements in fatigue and pruritus

Ipsen delivers strong sales momentum in the first nine months of 2024 and increases its full-year guidance

Ipsen’s Kayfanda® (odevixibat) approved in European Union for cholestatic pruritus in Alagille Syndrome, a rare liver disease

Ipsen’s Iqirvo® (elafibranor) approved in the European Union as first new treatment for primary biliary cholangitis in nearly a decade

Royal Bank of Canada

Royal Bank of Canada

Top News Gainers

4/20 Ipsen Announces Positive Topline Results From Pivotal Phase III CheckMate -9ER Trial Evaluating CABOMETYX® (cabozantinib) in Combination with Opdivo® (nivolumab) in Previously Untreated Advanced Renal Cell Carcinoma 5.8%

4/22 Ipsen Reports Solid Sales Growth in First Quarter 2020 With Limited COVID-19 Impact 5.5%

4/27 Photocure Regains Worldwide Rights of Hexvix 3.8%

5/20 IPSEN S A/S (OTCMKTS: IPSEY) was upgraded by analysts at JPMorgan Chase & Co. from an "underweight" rating to a "neutral" rating. 1.9%

7/23 Ipsen: Disclosure of Transactions in Own Shares Between 15/07/2019 And 19/07/2019 1.8%

5/28 Combined Shareholders’ Meeting of IPSEN S.A. held on 28 May 2019 1.3%

4/1 Ipsen Donates €2 Million to the Institut Pasteur to Support Research on COVID-19 1.2%

4/14 Ipsen: Monthly Information Regarding the Total Number of Voting Rights and Total Number of Shares of the Company 1.0%

6/17 IPSEN: Monthly Information Regarding the Total Number of Voting Rights and Total Number of Shares of the Company 1.0%

5/13 IPSEN: Monthly information regarding the total number of voting rights and total number of shares of the Company 1.0%

Top News Decliners

1/24 Ipsen’s palovarotene clinical program in fibrodysplasia ossificans progressiva reaches prespecified interim analysis futility criteria -23.2%

12/6 Ipsen Initiates Partial Clinical Hold for Palovarotene IND120181 and IND135403 Studies -13.7%

7/28 Ipsen S.A. ADR (IPSEY) CEO David Meek on Q2 2019 Results - Earnings Call Transcript [Seeking Alpha] -6.0%

1/9 IPSEN S A/S (OTCMKTS: IPSEY) was downgraded by analysts at Jefferies Financial Group Inc from a "buy" rating to a "hold" rating. -5.2%

12/18 Ipsen Announces Departure of David Meek as Chief Executive Officer -5.1%

12/6 Ipsen Plunges as FDA Halts Bone Drug Trial in Children on Safety Concerns [Yahoo! Finance News] -5.0%

3/3 IPSEN S A/S (OTCMKTS: IPSEY) was upgraded by analysts at Zacks Investment Research from a "sell" rating to a "hold" rating. -4.6%

2/13 Ipsen Presents Its 2019 Results, Provides 2020 Guidance and Updates 2022 Financial Outlook -4.2%

3/11 Ipsen Data Presented during ENETS Annual Conference 2020 Capture New Patient and Healthcare Professional Insights in the Treatment of NETs and Acromegaly -2.9%

3/17 Ipsen: Monthly Information Regarding the Total Number of Voting Rights and Total Number of Shares of the Company -2.7%

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