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Stock impact report

Novo weight loss therapy cuts mortality risk in kidney disease [Seeking Alpha]

Outset Medical, Inc. (OM) 
Company Research Source: Seeking Alpha
the risk of death by 20% in a study for patients with type 2 diabetes and chronic kidney disease. In October, the Danish drugmaker announced an early end to the trial named FLOW after an interim analysis showed early signs of success with semaglutide 1.0 mg. In reaction, shares of dialysis-related companies, including Fresenius ( FMS ), DaVita ( DVA ), Outset Medical ( OM ), and Baxter International ( BAX ), tumbled. In March, the company released more data from the study indicating that semaglutide 1.0 mg given as a weekly injectable with the standard of care achieved the study's primary endpoint, leading to a 24% reduction in the risk of kidney disease-related events. Novo's ( NVO ) rival in the weight loss space, Eli Lilly ( LLY ), whose obesity therapy tirzepatide is also undergoing studies for kidney-related ailments, trended lower after the announcement. The latest readout published in the New England Journal of Medicine and presented at a meeting of the European Renal Show less Read more
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