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Preliminary Analysis of Data Evaluating Investigational Epcoritamab (DuoBody® CD3xCD20) Combination Demonstrates 95% Overall Response Rate in Patients with Previously Untreated Follicular ...

Genmab A/S - American Depositary Shares (GMAB) 
Company Research Source: Yahoo! Finance
epcoritamab in combination with rituximab-lenalidomide (R ) experienced a 95% overall response rate (ORR) Results from the optimization cohort of the EPCORE™ NHL- 1 study show that mitigation strategies led to a clinically significant reduction in rate of cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) in patients with relapsed/refractory (R/R) FL treated with epcoritamab COPENHAGEN, Denmark, June 02, 2024 BUSINESS WIRE Genmab A/S (Nasdaq: GMAB) today announced new efficacy and safety data from two ongoing Phase 1/2 clinical trials evaluating epcoritamab, a T-cell engaging bispecific antibody administered subcutaneously, in adult patients with certain types of follicular lymphoma (FL). A preliminary analysis of data from the EPCORE™ NHL-2 study ( NCT04663347 ), evaluating epcoritamab in combination with rituximab-lenalidomide (R ), demonstrated an overall response rate (ORR) of 95% and complete response rate (CRR) of 85% in patien Show less Read more
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