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Stock impact report

Genmab acquires biotechnology company ProfoundBio in $1.8bn deal [Yahoo! Finance]

Genmab A/S - American Depositary Shares (GMAB) 
Company Research Source: Yahoo! Finance
ProfoundBio specialises in the development of antibody-drug conjugates (ADCs) and technologies for cancer treatment. The latest development comes after the companies signed a definitive agreement for the acquisition in April 2024. Genmab obtained global rights to ProfoundBio's portfolio of next-generation ADCs, significantly bolstering its clinical pipeline. These programmes include Rina-S, an ADC being analysed in Part II of a Phase I/II clinical trial to treat ovarian cancer and other FRa-expressing solid tumours. The ongoing Phase I/II clinical trial data suggests that Rina-S could serve a wider patient demographic than the first-generation FRa-targeted ADCs. Genmab is planning to expand the development of Rina-S within ovarian cancer and other FRa-expressing solid tumours based on these findings. In January 2024, Rina-S received fast-track designation from the US Food and Drug Administration (FDA) to treat patients with FRa-expressing high-grade serous or endometrioid Show less Read more
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